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. Author manuscript; available in PMC: 2008 Dec 1.
Published in final edited form as: Pharmacol Res. 2007 Oct 2;56(6):531–541. doi: 10.1016/j.phrs.2007.09.017

Figure 1.

Figure 1

Prostaglandin E1 and its potential degradation products. In vivo metabolism of PGE1 results in the formation of 13,14-dihydro-15-keto PGE1. PGA1 is a non-enzymatic decomposition product of PGE1. While 15-keto PGE1 is readily formed from PGE1 in vivo, its formation in vitro requires strong oxidizing agents.