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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Mol Cell Neurosci. 2007 Nov 1;37(2):376–387. doi: 10.1016/j.mcn.2007.10.014

Figure 9.

Figure 9

The calpain inhibitor, calpeptin, rescues SGN neurites from growth inhibition by depolarization. A. Cumulative percent histograms of SGN neurite lengths from cultures maintained in NT-3, NT-3+30K, or NT-3+80K with or without calpeptin (Calp,10 μM) as indicated. Each condition was repeated three times. NT-3+30K and NT-3+80K are significantly different (p<0.05) from NT-3+30K+Calp and NT-3+80K+Calp, respectively, by Kruskal-Wallis ANOVA on Ranks followed by a Dunn’s post-hoc comparison. n=cumulative number of SGNs scored for each condition B–C. Representative images of spiral ganglion cultures maintained in NT-3+30K or NT-3+30K+Calp (B) and NT-3+80K or NT-3+30K+Calp (C) for 48 h and labeled with anti-NF-200. Scale bar=100 μm.