Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2008 Mar 10;180(5):947–955. doi: 10.1083/jcb.200709069

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2008, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 3. — Hypomyelination in the CNS of the of b-raf^Δ/Δneu mice. Electron micrographs of P18 optic nerves (A) and spinal cords (B) in cross section. Note the high proportion of unmyelinated axons (plotted on the right as mean ± SD for the optic nerve; *, P < 0.05 comparing b-raf ^f/f and b-raf ^Δ/Δneu mice) and the thinner myelin sheaths in b-raf ^Δ/Δneu sections. The scatter plots show g ratios (diameter of the axon proper:outer diameter of the myelinated fiber) as a function of axon diameter for optic nerve and spinal cord (100 axons/mouse, three b-raf ^f/f, and three b-raf ^Δ/Δneu mice). White symbols indicate WT and gray symbols indicate b-raf ^Δ/Δneu mice. g ratios are higher in the b-raf ^Δ/Δneu mice (P < 0.0005), which indicates hypomyelination. Bars, 2.5 μm.