Table 1. Datasets used in this study.
Author | Reference | Source of integrations | Number of sites | Use of Sites |
Derse et al. | 22 | In vitro infection of HeLa cells with virus like particles | 527 | Comparison of in vitro and in vivo integration sites (Fig 1). |
Meekings et al. | This Study | In vitro infection of Jurkat cells by co-culture with infected cell line | 266 | Comparison of in vitro and in vivo integration sites (Fig 1). |
Meekings et al. | This Study | In vivo infected PBMCs isolated from naturally infected HAM/TSP patients and Acs blood samples | 313 | Comparison of in vitro and in vivo integration sites (Fig 1). Investigation of the association of the distribution of integration sites and Tax expression between individuals (Fig 3). |
Meekings et al. | This Study | Flow cytometric sorting of provirus expressing vs. non-expressing naturally infected patient PBMCs | 40 | Investigation of the association of the distribution of integration sites and Tax expression within an individual (Fig 4) |