Table 1. Immunodominant peptides of Ag 85 A from M. ulcerans and M. tuberculosis.
Peptides : aa | Sequences of M. ulcerans * | Sequences of M. tuberculosis |
21–40 | NIKVQFQSGGANSPALYLLD | DIKVQFQSGGANSPALYLLD |
61–80 | yyqsgisvampvggqssfys | YDQSGLSVVMPVGGQSSFYS |
81–100 | dwynpacgkagcttykwetf | DWYQPACGKAGCQTYKWETF |
141–160 | dqfvysgslsalldpsqg ig | QQFVYAGAMSGLLDPSQA MG |
240–259 | FQAAYNAAGGHNAVWNFDDN | 85A :FQDAYNAGGGHNGVFDFPDS |
85B :FQDAYNAAGGHNAVFNFPPN | ||
261–280 | thsweywgaqlnamrpdlqh | THSWEYWGAQLNAMKPDLQR |
275–294 | rpdlqhtlgatpntgdtqga | KPDLQRALGATPNTGPAPQGA |
*: Bold Amino Acids are high conserved amino acid differences (determined according to the Needleman-Wunsh criterion) and Amino Acids underlined are the non-conserved aa difference in comparison to the Ag85A peptides of M. tuberculosis.