Skip to main content
. 2008 Feb 29;4(2):e1000004. doi: 10.1371/journal.pcbi.1000004

Table 1. Parameter values used in both stochastic and deterministic simulations.

Constant Value Description
Rm 0.57 Ωm2 membrane resistance
Cm 0.03 F/m2 membrane capacitance
Em −0.025 V equilibrium membrane potential
Inline graphic +0.07 V equilibrium potential for Na+
Inline graphic −0.075 V equilibrium potential for K+
Inline graphic +0.14 V equilibrium potential for Ca2+
Inline graphic −0.085 V equilibrium potential for BKCa
B 5.2⋅10−6 mol/C constant for Ca2+ transfer into the cell
[Ca2+]rest 100⋅10−6 mol/m3 [Ca2+] at rest
τCa 1⋅10−3 s time constant for the decay of
intracellular free calcium
dcell 6⋅10−6 m diameter of the granule cell
dshell 1⋅10−7 m diameter of the shell defining the volume
in which calcium ions are processed
Inline graphic 400 S/m2 maximal conductance for NaF
Inline graphic 120 S/m2 maximal conductance for KDr
Inline graphic 10 S/m2 maximal conductance for KA
Inline graphic 28 S/m2 maximal conductance for Kir
Inline graphic 4.6 S/m2 maximal conductance for CaHVA
Inline graphic 30 S/m2 maximal conductance for BKCa
Inline graphic 3 exponential for NaF activation
Inline graphic 1 exponential for NaF inactivation
Inline graphic 4 exponential for KDr activation
Inline graphic 3 exponential for KA activation
Inline graphic 1 exponential for KA inactivation
Inline graphic 1 exponential for Kir activation
Inline graphic 2 exponential for CaHVA activation
Inline graphic 1 exponential for CaHVA inactivation
Inline graphic 1 exponential for BKCa activation

See the sections Deterministic Model and Complete Stochastic Model for more details on ion channel types and the description of the complete mathematical model.