Table 3. Quantitative analysis of the interspike intervals of the stochastic model.
Depolarizing current | σ | mean (s) | std (s) | CV |
Iapp = 11 pA | 0.1 | 0.0536 | 0.0461 | 0.8598 |
0.3 | 0.0251 | 0.0155 | 0.6194 | |
0.5 | 0.0205 | 0.0124 | 0.6055 | |
Iapp = 12 pA | 0.1 | 0.0247 | 0.0130 | 0.5282 |
0.3 | 0.0208 | 0.0118 | 0.5655 | |
0.5 | 0.0184 | 0.0106 | 0.5794 | |
Iapp = 29 pA | 0.1 | 0.0036 | 4.53⋅10−5 | 0.0125 |
0.3 | 0.0036 | 1.24⋅10−4 | 0.0343 | |
0.5 | 0.0036 | 2.04⋅10−4 | 0.0562 |
Firing is simulated for 50 seconds with three different values of depolarizing current pulses, Iapp, and the parameter σ. The chosen levels for depolarizing current pulses are: i) Iapp = 11 pA (below firing threshold, Ith), ii) Iapp = 12 pA (just above the firing threshold), and iii) Iapp = 29 pA (a considerably larger stimulus). From each trace the mean, standard deviation (std) and the coefficient of variation (CV) of the interspike intervals are calculated. Seconds are used as units for the mean and standard deviation; coefficient of variation is dimensionless. Same simulated data is used as in Figure 8.