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. 2008 Feb 29;4(2):e1000009. doi: 10.1371/journal.pcbi.1000009

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Montiel Molina et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Combined Sensitivity (CS) is plotted against the Root Mean Square Deviation (RMSD) values observed for every pair of structures compared. 31 HIV-1 protease structures in complex with a substrate were compared against 42 HIV-1 protease structures without a substrate. Please refer to Methods for the PDB codes of the structures used in this comparison.