Table 2. Statistical Analysis of the TBP Functional Conformer Identification.

Group	N	Mean	SD
TBP+WtDNA	63000	0.254	0.122
TBP-WtDNA	63000	0.249	0.116
TBP-GCDNA	63000	0.234	0.117
TBP	63000	0.23	0.109

(Upper Part) Each row shows the statistical parameters for each group of TBP conformers derived from molecular dynamics simulations. TBP+WtDNA: TBP with the TATA sequence. TBP-WtDNA: TBP orginally resolved with the TATA sequence but removed during the simulation. TBP-GCDNA: TBP with a GCGC sequence. TBP: TBP originally resolved without DNA and simulated without DNA. (N: number of conformers, SD: Standard deviation).

(Lower Part) Each row summarizes the results for a one-way ANOVA (Null hypothesis: mean(1st group) = mean(2nd group)) for the pairs of groups indicated in the first column. In each case the null hypotheses is rejected at the 0.05 level of significance (DF: degrees of freedom, MS:mean square, F: Calculated F-value , α: level of significance).