Dependence of KWII for case study 2 on the LD R2 between SNP 1 and SNP 2. A–C, KWII spectra for three representative R2 values of 0, 0.5, and 0.95, respectively. The combinations used for KWII calculations are indicated on the Y-axes. The error bars represent SDs that are due to sampling and were obtained from 100 random samples. D, Dependence of KWII (unblackened symbols) and TCI (blackened symbols) for the one-variable–containing peak T1 (circles), the two-variable–containing peak T2 (triangles), and the three-variable–containing interaction peak T3 (squares). The error bars represent SDs.