Table 2. .

Summary of Statistically Significant Single-SNP Results from the PDT^[Note]

SNP	Nucleotide Position	SNP Name	Genotype	GRRa (95% CI)	Z	Pb
16	411873	IGR2008a_1	C/C	2.15 (1.26–3.67)	2.82	.0047
26*	435282	IGR2055a_1	G/G	2.14 (1.30–3.53)	3.00	.0027
27*	437682	IGR2060a_1	C/C	2.19 (1.31–3.65)	2.99	.0028
28*	438883	IGR2063b_1	G/G	2.21 (1.34–3.64)	3.11	.0019
34*	455246	IGR2096a_1	C/C	.35 (.17–.72)	−2.88	.0039
39*	506266	IGR2198a_1	G/G	2.32 (1.44–3.75)	3.46	.00055
49	522600	IGR2230a_1	T/T	2.40 (1.35–4.28)	2.96	.003
56	571022	IGR3005a_2	G/G	1.99 (1.25–3.15)	2.92	.0035
57	576586	IGR3016a_1	G/G	2.36 (1.36–4.09)	3.04	.0023
65*	582948	IGR3029a_2	G/G	2.25 (1.40–3.61)	3.37	.00076
67*	587836	IGR3039a_1	A/A	1.92 (1.21–3.06)	2.76	.0058
74*	608759	IGR3081a_1	T/T	.36 (.17–.74)	−2.79	.0053
78*	616241	IGR3096a_1	T/T	.34 (.16–.73)	−2.80	.0052
86	649061	IGR3162a_1	G/G	.21 (.06–.72)	−2.48	.013
90	662819	IGR3189a_2	T/T	.29 (.12–.72)	−2.68	.0073
91*	676688	IGRX100a_1	A/A	1.97 (1.17–3.32)	2.55	.011
92	683387	IGR3230a_1	T/T	.37 (.17–.78)	−2.60	.0094
93*	686249	IGR3236a_1	G/G	.39 (.21–.75)	−2.83	.0046
102*	877809	GENS020ex3_1	C/C	.42 (.24–.73)	−3.05	.0023

Note.— SNPs identified by Rioux et al.¹⁷ are shown in bold, and SNPs identified by the KWII are identified by an asterisk (*).

^aGenotype relative risk, in which the reference genotype is the heterozygote.

^bAll P values are significant after correction for multiple testing with use of the method of Benjamini and Hochberg.³²