Figure 5. .

Classification and quantification of morphological phenotypes. Embryos aged 27 h injected with GDF1 constructs were sorted into classes I–IV (from wild type [WT] to those with the severest developmental defects) and were quantified. All mutant constructs exhibited varying degrees of decreased activity compared with WT humanized GDF1. mGDF1 = murine GDF1. Red font indicates the predominant class.