Table 2. .
Error Rate(%) |
|||||||||
Low-Density Simulateda |
High-Density Simulateda |
Affymetrix 500K WTCCCb |
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Method | Small | Medium | Large | Small | Medium | Large | Small | Medium | Large |
Beaglec: | |||||||||
R=25 | 3.45 | 1.91 | 1.57 | 1.17 | .53 | .13 | 1.21 | .87 | .77 |
R=4 | 3.65 | 2.01 | 1.57 | 1.36 | .59 | .13 | 1.32 | .88 | .78 |
R=1 | 4.10 | 2.21 | 1.80 | 1.82 | .70 | .16 | 1.44 | .94 | .84 |
fastPHASEd: | |||||||||
K=20 | 3.37 | 2.54 | 2.80 | 1.19 | .90 | .57 | 1.12 | .95 | .93 |
K=10 | 3.91 | 3.19 | 3.43 | 1.72 | 1.38 | 1.04 | 1.21 | 1.05 | 1.04 |
HAP | 5.26 | 3.66 | 3.89 | 3.20 | 2.55 | 2.31 | 1.68 | 1.38 | 1.33 |
2SNP | 8.52 | 5.76 | 5.14 | 3.61 | 2.33 | 1.26 | 2.50 | 1.84 | 1.71 |
Parameters for selection of tag SNPs for 1 Mb of simulated data were chosen to obtain approximate densities of 1 SNP per 10 kb (low density) or 1 SNP per 3 kb (high density). For each density, three sample sizes were considered: 100 (small), 1,000 (medium), and 5,000 (large) individuals.
For the WTCCC data, sets of 200 consecutive markers were used. Three sample sizes were considered: 100 (small), 1,000 (medium), and 3,002 (large) individuals.
Beagle results are given for R=1, R=4, and R=25 samples per individual.
fastPHASE results are given for K=10 and K=20 clusters per individual.