Table 1.
Single amino acid differences found across plasma and diverse blood leukocyte population in vivo.
| HXB2 | CD4+ | CD8+ | Monocytes | PBMC | Plasma |
| 279 | Asparagine (N) | Aspartic acid (D) | |||
| 336 | Threonine (T) | Alanine (A) | |||
| 335 | Arginine (R) | Lysine (K) | Arginine (R) | ||
| 350 | Arginine (R) | Lysine (K) | Arginine (R) | ||
| 320 | Alanine (A) | Threonine (T) | Alanine (A) | ||
| 440 | Arginine (R) | Serine (S) | Arginine (R) | ||
| 360 | Isoleucine (I) | Alanine | Valine(v) | Alanine (A) | |
Each column represents a particular compartment from which sequences were derived. Distinct signature pattern differences are shown in the rows with the corresponding amino acid variations. The locations of these variations are aligned with those of the HIV-1 HXB2 reference strain using the guidelines available on the HIV Database website, Los Alamos, NM, USA [18].