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. Author manuscript; available in PMC: 2009 Feb 19.
Published in final edited form as: Neuroscience. 2008 Jan 16;151(4):1034–1041. doi: 10.1016/j.neuroscience.2007.12.015

Fig. 5.

Fig. 5

NGF signals are transmitted through PI3K to enhance AP2 reporter activity. PC12 cells were transfected with reporter constructs of the full length P2 K18 (A) and AP2 Kd50 (B), and treated with NGF for 24 h, or NGF in the presence of U73122 (U73) or LY294002 (LY29). Each luciferase reading was normalized to the internal control reading. The value of the control (con) group was arbitrarily set at 1 and the value of each experimental group was plotted as fold induction and SD by comparing to the control. The data were collected from three independent experiments. Column NGF *p<0.01 versus control, column LY294002 **p<0.05 versus NGF for both constructs.