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. 2006 Dec 1;119(4):507–514. doi: 10.1111/j.1365-2567.2006.02465.x

Figure 2.

Figure 2

HPV-16 (a) L1- and (b) E7-specific IFN-γ production by CD4+ and CD8+ T cells from all donors following direct ex vivo stimulation. Individual donors have been grouped according to whether they were (i) actively infected with HPV-16 (DNA Positive; bottom panel) or (ii) were negative for HPV-16 DNA (top panel). Within each of these groups, individual donors have been grouped according to CIN status and serum IgG status. Each bar represents an individual's net percentage IFN-γ production by either CD4+ or CD8+ CD3+ T cells. Net percentage IFN-γ responses were calculated by subtracting background percentage IFN-γ production by unstimulated cells.