Figure 8.

Normal differentiation to B and T cells of MOP3^–/– BMC in MOP3^+/+ BALB/c Rag2^–/– recipients. Four months after Rag2^–/– mice received lethal X-rays irradiation and an injection of T-cell depleted MOP3^+/+ or MOP3^–/– BMC, the levels of T, B and other immune cells in peripheral blood, spleens and bone marrow were determined by two-colour FCM. (a) The levels of T and B subsets in spleens of Rag2^–/– mice received either MOP3^+/+ or MOP3^–/– BMC. (b) The percentages of B-cell subpopulations in bone marrow of Rag2^–/– mice received MOP3^+/+ or MOP3^–/– BMC. Data were presented as mean ± SD. Two independent experiments showing similar results were performed. No significant differences were found among the identical groups (P > 0·05).