Figure 9.

Decreased B-cell differentiation of allogeneic BMCs in MOP3^–/– recipients. Eight weeks after transplantation of T-cell depleted allogeneic BALB/c MOP3^+/+ BMC to lethally irradiated MOP3^–/– BMC, the levels of donor T and B cells in spleens and bone marrow were determined by three-colour FCM. (a) The levels of B-cell subsets in spleens of either MOP3^+/+ or MOP3^–/– recipients received BALB/c BMC. (b) The percentages of B cell subpopulations in the bone marrow of MOP3^+/+ or MOP3^–/– recipients received BALB/c BMC. Data were presented as mean ± SD. *P < 0·05 compared between the indicated groups. Six mice were used in each group.