Table 2.
Haemodynamics in the HEV microcirculation of murine cervical lymph nodes
| RBC flow velocity | Wall shear rate | ||
|---|---|---|---|
| C57BL/6 wild-type | (n = 6) | 0·8 ± 0·1 | 82 ± 10 |
| LFA-1-deficient | (n = 7) | 0·7 ± 0·1 | 81 ± 9 |
| Ethanol-treated | (n = 9) | 0·8 ± 0·1 | 78 ± 15 |
| Simvastatin-treated | (n = 9) | 0·7 ± 0·1 | 66 ± 19 |
| Vehicle-treated | (n = 8) | 0·7 ± 0·1 | 78 ± 12 |
| LFA878-treated | (n = 8) | 0·6 ± 0·1 | 66 ± 13 |
| LFA703-treated | (n = 8) | 0·7 ± 0·1 | 81 ± 7 |
Intravital microscopic images were televised and centreline red blood cell (RBC) flow velocity (mm/second) as well as wall shear rates (per second) were quantitatively analysed off-line. Data are mean values ± standard error of the mean and n represents the number of animals per group.