Skip to main content
. 2007 May;121(1):105–112. doi: 10.1111/j.1365-2567.2007.02543.x

Figure 1.

Figure 1

Diagrams depicting structure of HBV SCTs and chimeric DNA and vaccinia virus constructs. (a) SCT which includes a signal peptide, epitope, β2m and human MHC-I molecule HLA-A2 was linked by a 15 amino acid GS linker. (b) SCTs containing HBcAg epitope C18−27 (pcDNA3.0-SCT-C18−27, FLPSDFFPSV), epitope C107−115 (pcDNA3-SCT-C107−115, CLTFGRETV) and a control epitope from HIV gag (SLYNTVATL) were cloned into pCDNA3.0 vector separately to make the DNA vaccine in the study. (c) Diagram of transfer vector AE-SCT-C18−27, which includes an EGFP gene and SCT-C18−27 gene. (d) Transfer vectors AE (control vaccinia vector with EGFP), AE-SCT-C18−27 and AE-SCT-C107−115 were constructed and recombined with wild-type vaccinia virus TianTan strain (VTT) to make recombinant vaccinia virus (rVTT) in this study.