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. 2007 Nov;122(3):350–361. doi: 10.1111/j.1365-2567.2007.02646.x

Figure 2.

Figure 2

Activation of IFN-γ, IL-4 and IgG1 anti-BCG antibodies by BCG infection and influence of IL-12p40 overexpression. Kinetics of serum (a) and spleen (b) levels of IFN-γ induced by BCG infection. Amounts of IL-4 (c) in spleen of IL-12p40 tg and control mice after BCG infection. IL-4 was not detectable (ND) at 2 weeks of infection. Data are represented as means ± SEM (pg of protein/ml of serum or pg of protein/spleen) (n = 5–9 mice/group). Kinetics of IgG1 anti-BCG (d) antibodies at different time points after BCG infection. Results are represented as relative OD values after subtraction of unspecific OD corresponding to serum before infection. Data are represented as means ± SEM (n = 5–6 mice/group). These results are representative of two independent experiments (a to c) or one experiment (d). *P < 0·006.