Figure 7.

Effects of IFN-β on intrasinusoidal haemostasis induced by Con A administration. Paraffin sections from the livers removed at 3 hr after Con A injection with pretreatment of saline (a) or IFN-β (b) were stained with haematoxylin & eosin (original magnification: ×400). Under ether anaesthesia, intrasinusoidal blood flow was measured using a laser–Doppler flow meter at 3 hr after Con A injection with IFN-β administration, and data were expressed as a percentage on the non-treated mice (c) Data represent the mean ± SEM (n =5). *P < 0·05 non-treatment group or IFN-β + Con A group versus saline + Con A group by t-test.