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. 2007 Dec;122(4):623–633. doi: 10.1111/j.1365-2567.2007.02709.x

Figure 1.

Figure 1

Induction of 150-kDa adenosine deaminase that acts on RNA 1 (ADAR1) gene expression in T cells by anti-CD3-ε plus anti-CD28 activation. An ethidium bromide-stained agarose gel is shown demonstrating polymerase chain reaction (PCR)-amplified 110-kDa and 150-kDa ADAR1, interleukin (IL)-2 and β-actin gene transcripts at various time-points of T-cell activation by anti-CD3-ε plus anti-CD28. All lanes contain PCR products derived from 10% of cDNA synthesized from 1 µg of total RNA isolated from control and activated T cells at time-points ranging from 0 to 48 hr. The 150-kDa ADAR1 mRNA expression was up-regulated at the 18-hr time-point and had reached control levels by the 48-hr time-point.