Table 4.
Clinical tests of Control Group
| Unit | Before | 8 weeks later | P value vs “before” value | P value vs Test Group | |
|---|---|---|---|---|---|
| Leukocyte Count (WBC) | /µl | 7244.0 ± 2665.9 | 6456.7 ± 2120.0 | 0.020 | 0.335 |
| Erythrocyte Count (RBC) | 104/µl | 468.6 ± 40.0 | 464.7 ± 42.0 | 0.477 | 0.865 |
| Hemoglobin Content (HGB) | g/dl | 14.2 ± 1.6 | 14.2 ± 1.7 | 0.768 | 0.497 |
| Hematocrit (HCT) | % | 43.3 ± 3.7 | 43.4 ± 3.8 | 0.863 | 0.741 |
| Mean Corpuscular Volume (MCV) | fl | 92.6 ± 5.6 | 93.5 ± 5.7 | 0.038 | 0.736 |
| Mean Corpuscular Hemoglobin (MCH) | pg | 30.4 ± 2.6 | 30.5 ± 2.7 | 0.293 | 0.270 |
| Mean Corpuscular Hemoglobin Concentration (MCHC) | % | 32.8 ± 1.3 | 32.6 ± 1.3 | 0.309 | 0.568 |
| Platelet count | 104/µl | 26.4 ± 4.5 | 26.5 ± 5.6 | 0.810 | 0.867 |
| Glutamate Oxaloacetate Transaminase (GOT) | U/l | 23.4 ± 5.3 | 22.3 ± 5.5 | 0.408 | 0.974 |
| Glutamate Pyruvate Transaminase (GPT) | U/l | 27.3 ± 11.3 | 26.3 ± 11.0 | 0.618 | 0.992 |
| Alkaline phosphatase (ALP) | U/l | 251.3 ± 71.2 | 244.0 ± 63.8 | 0.443 | 0.889 |
| γ-glutamyl transpeptase (γ-GTP) | U/l | 49.1 ± 40.2 | 50.7 ± 47.7 | 0.736 | 0.790 |
| Blood Creatinine (Cr) | mg/dl | 0.68 ± 0.15 | 0.69 ± 0.15 | 0.241 | 0.962 |
| Blood Urea Nitrogen (BUN) | mg/dl | 14.3 ± 3.7 | 14.2 ± 2.6 | 0.923 | 0.587 |
| Uric acid (UA) | mg/dl | 5.59 ± 1.26 | 5.64 ± 1.14 | 0.799 | 0.570 |
| Creatine Phosphokinase (CPK) | mg/dl | 138.6 ± 91.0 | 183.9 ± 251.4 | 0.327 | 0.429 |
| Total cholesterol | mg/dl | 224.6 ± 47.2 | 230.5 ± 50.8 | 0.346 | 0.887 |
| HDL-cholesterol | mg/dl | 51.5 ± 7.8 | 55.6 ± 11.2 | 0.069 | 0.525 |
| LDL-cholesterol | mg/dl | 147.6 ± 46.3 | 148.1 ± 43.7 | 0.910 | 0.691 |
| Triglycerides (TG) | mg/dl | 173.4 ± 147.7 | 132.3 ± 57.7 | 0.259 | 0.905 |
| Na | mEq/l | 142.4 ± 1.2 | 142.9 ± 1.2 | 0.150 | 0.983 |
| K | mEq/l | 4.21 ± 0.30 | 4.13 ± 0.26 | 0.395 | 0.882 |
| Cl | mEq/l | 104.1 ± 1.6 | 104.4 ± 2.0 | 0.658 | 0.905 |
| Fasting Blood Sugar (FBS) | mg/dl | 92.9 ± 9.4 | 94.3 ± 10.3 | 0.576 | 0.615 |
| Glycohemoglobin A1C (HbA1c) | % | 4.89 ± 0.40 | 5.03 ± 0.43 | 0.001 | 0.799 |
| C-Reactive Protein (CRP) | mg/dl | 0.19 ± 0.10 | 0.17 ± 0.11 | 0.262 | 0.685 |
| Lactic acid | mg/dl | 8.17 ± 3.45 | 9.56 ± 3.51 | 0.173 | 0.471 |
| Lipid peroxide (LPO) | nmol/ml | 0.65 ± 0.99 | 0.32 ± 0.08 | 0.216 | 0.802 |
| Insulin | µU/ml | 9.00 ± 7.13 | 7.93 ± 3.83 | 0.543 | 0.648 |
| IGF-I | ng/ml | 197.9 ± 68.9 | 180.6 ± 60.4 | 0.007 | 0.636 |
| Cortisol | µg/dl | 9.9 ± 3.0 | 10.2 ± 6.8 | 0.873 | 0.562 |
| Dehydroepiandrosterone Sulfate (DHEA-s) | ng/ml | 2034.1 ± 1136.3 | 1928.3 ± 899.5 | 0.474 | 0.993 |
| 8-hydroxy-deoxyguanosine (8-OHdG) generation | ng/kg/hr | 9.45 ± 7.41 | 8.85 ± 4.59 | 0.282 | 0.549 |
| Isoprostane generation | ng/kg/hr | 142.2 ± 88.7 | 138.1 ± 85.5 | 0.336 | 0.427 |
| 8-OHdG/CRE | ng/mgCRE | 116.0 ± 73.9 | 128.5 ± 71.7 | 0.233 | 0.353 |
| Isoprostane/CRE | ng/mgCRE | 1846.1 ± 869.6 | 1837.8 ± 1117.4 | 0.377 | 0.338 |
n = 17, mean ± SD, paired t test or Mann-Whitney U test