Reaction time (A) and number of lapses (B) (on the Psychomotor Vigilance Test [PVT[) and mean variation in speed (C) and lane position (D) at 0.03% blood alcohol concentration (BAC) (▴) and 0.00% BAC (●) in a non–sleep-deprived state and after extended wakefulness. There was a significant increase in reaction time, number of lapses, and variation in lane position with extended wakefulness in the alcohol condition only (F1.85, 25.94 = 14.66, P < 0.001; F1.44, 20.13 = 4.80, P < 0.05; and F1.93, 27.05 = 13.15, P < 0.001, respectively). Variation in speed increased with extended wakefulness in both the alcohol (F1.51, 21.10 = 6.33, P < 0.05), and no-alcohol conditions (F2.28, 31.94 = 3.63, P < 0.05). Error bars represent SEM. *P< 0.05.