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. 2005 Sep;126(3):285–299. doi: 10.1085/jgp.200509289

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Copyright © 2005, The Rockefeller University Press

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Figure 1. — Mutations at position 334 disrupt ATP inhibition of K_ir6.2ΔC26 channels. Response to indicated concentration of ATP of channels representative of strong and moderate disruption of ATP sensitivity is shown. NP_O was determined at the different concentrations of ATP including 0 ATP. The strongest effects were obtained for the negative-charged aspartate and glutamate. The weakest effects were observed with the positive-charged arginine and lysine.