TABLE I.
Parameter | HM | aHM | SBS | aSBS | EMG | aEMG | JBS | AG |
---|---|---|---|---|---|---|---|---|
KCa WT (μM) | 0.29 ± 0.03 | 0.39 ± 0.04 | 0.30 ± 0.03 | 0.66 ± 0.13 | 1.36 ± 0.08 | 0.60 ± 0.09 | 1.18 ± 0.16 | 0.50 ± 0.15 |
KCa QM(μM) | 21.2 ± 4.3 | |||||||
KCa SM (μM) | 39.8 ± 4.0 | 89 ± 14 | 670 ± 99 | |||||
KCa M(μM) | 112 ± 12 | 215 ± 40 | 15000a | 15000a | 1423 ± 135 | 471 ± 125 | 1379 ± 235 | |
f | 0.12 ± 0.02 | 0.27 ± 0.03 | 0.046 ± 0.020 | |||||
KO0 | 851b | 33.21b | 10800b | 100a | ||||
KO1 | 0.176b | |||||||
KO4 | 0.176b | 0.176b | 0.176b | 0.176b | 0.00219b | 0.048b | ||
KOL | 0.5a | 0.5 a | ||||||
KCL | 0.0333a | 0.89 ± 0.52 | ||||||
KCI | 3a | 3a | ||||||
KCa I(μM) | 0.1a | |||||||
KA | 0.47 ± 0.13 | |||||||
Variable | HM | aHM | SBS | aSBS | EMG | aEMG | JBS | AG |
PO min | 0 | 0.0011 | 0 | 0.029 | 0 | 0.0001 | 0 | 0 |
χ2 | 160.9 | 94.7 | 196.0 | 113.6 | 132.6 | 82.0 | 97.5 | 170.6 |
df | 74 | 72 | 74 | 73 | 74 | 71 | 73 | 73 |
P | 2.2 × 10−8 | 0.038 | 5.7 × 10−13 | 0.0017 | 3.4 × 10−5 | 0.17 | 0.029 | 8.7 × 10−10 |
Errors are shown as standard error of the fit. PO min, open probability in the absence of Ca2+; χ2, chi-square value; df, degrees of freedom; P, probability that the differences between data and model are due to random deviations.
Constant parameters.
Parameters calculated from the remaining parameters and from the value of PO max = 0.85.