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. 2005 Nov;126(5):515–527. doi: 10.1085/jgp.200509328

TABLE I.

The Parameters and Goodness of Fit of Model Gating Schemes

Parameter HM aHM SBS aSBS EMG aEMG JBS AG
KCa WT (μM) 0.29 ± 0.03 0.39 ± 0.04 0.30 ± 0.03 0.66 ± 0.13 1.36 ± 0.08 0.60 ± 0.09 1.18 ± 0.16 0.50 ± 0.15
KCa QM(μM) 21.2 ± 4.3
KCa SM (μM) 39.8 ± 4.0 89 ± 14 670 ± 99
KCa M(μM) 112 ± 12 215 ± 40 15000a 15000a 1423 ± 135 471 ± 125 1379 ± 235
f 0.12 ± 0.02 0.27 ± 0.03 0.046 ± 0.020
KO0 851b 33.21b 10800b 100a
KO1 0.176b
KO4 0.176b 0.176b 0.176b 0.176b 0.00219b 0.048b
KOL 0.5a 0.5 a
KCL 0.0333a 0.89 ± 0.52
KCI 3a 3a
KCa I(μM) 0.1a
KA 0.47 ± 0.13
Variable HM aHM SBS aSBS EMG aEMG JBS AG
PO min 0 0.0011 0 0.029 0 0.0001 0 0
χ2 160.9 94.7 196.0 113.6 132.6 82.0 97.5 170.6
df 74 72 74 73 74 71 73 73
P 2.2 × 10−8 0.038 5.7 × 10−13 0.0017 3.4 × 10−5 0.17 0.029 8.7 × 10−10

Errors are shown as standard error of the fit. PO min, open probability in the absence of Ca2+; χ2, chi-square value; df, degrees of freedom; P, probability that the differences between data and model are due to random deviations.

a

Constant parameters.

b

Parameters calculated from the remaining parameters and from the value of PO max = 0.85.