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. 2005 Nov;126(5):529–538. doi: 10.1085/jgp.200509377

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Copyright © 2005, The Rockefeller University Press

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Figure 3. — HERG current expressed in HEK293 cells. (A) Tail current recordings at different potentials. Currents were elicited by depolarizing pulses at +20 mV followed by hyperpolarizing pulses (from 0 to −80 mV). (B) Currents remaining after treatment with 10 μM E-4031. (C) Current–voltage curves of tail currents before (black symbols) and after (red symbols) the treatment of E-4031 measured at 50 ms after the steps to repolarizing potentials.