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. 2005 Oct;126(4):393–412. doi: 10.1085/jgp.200509346

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Copyright © 2005, The Rockefeller University Press

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Figure 3. — BK_Ca gating currents. (Top traces) Gating current families recorded from BK_α (A) and BK_α+β1 (B) channels with 0.5 nM internal Ca²⁺. The second and third traces in A and B demonstrate that gating currents are not observed in patches from oocytes that were not injected with BK_Ca cRNA (second) or with hyperpolarizing voltage steps (third). The lowest traces in A and B are gating currents recorded with pulses to +160 mV. Repolarizations are to −80 mV. Exponential fits to the on and off currents are indicated with dashed line. (C and D) Comparisons of on-gating current (I_g) and potassium current (I_K) from BK_α (C) and BK_α+β1 (D) channels. Pulses were to +160 mV. Ca²⁺ = 0.5 nM. The gating and ionic currents compared in C and D are from different patches.