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. 2005 Oct;126(4):393–412. doi: 10.1085/jgp.200509346

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Copyright © 2005, The Rockefeller University Press

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Figure 4. — The β1 subunit shifts the closed channel's charge–voltage (Q–V) relation leftward without changing its shape. (A) On and Off Q–V relations determined from a single BK_α channel patch. (B) On and Off Q–V relations determined from a single BK_α+β1 channel patch. (C) Normalized averaged Q_on–V relations for the BK_α (11 curves averaged) and BK_α+β1 channels (14 curves averaged). Each curve in C is fitted with a Boltzmann function. The fit parameters are as follows: BK_α: z _J = 0.577 ± 0.023e, V _hc = 151 ± 1.9 mV; BK_α+β1: z _J = 0.571 ± 0.025 e, V _hc = 80 ± 2.4 mV. The error bars in C represent SEM.