Table 2.

Multipoint LOD scores (exceeding 1.0) across DSM-IV dependence criteria of alcohol and illicit drugs.

Chromosome	Position (cM)	Alcohol			Cannabis			Any Illicit			Alcohol & Drug
		LOD	P-value Observed	Empirical	LOD	P-value Observed	Empirical	LOD	P-value Observed	Empirical	LOD	P-value Observed	Empirical
1	213	2.0	.0011	0.62	-	-	-	-	-	-	1.4	.006	0.94
2	234	3.4	.00004	0.10	-	-	-	-	-	-	3.2	.00006	0.10
10	60	3.7	.00002	0.06	-	-	-	-	-	-	2.4	.0004	0.35
	99	1.8	.002	0.77	-	-	-	-	-	-	2.3	.0006	0.41
	116	1.7	.003	0.84	1.2	.008	0.98	2.0	.0014	0.60	2.6	.0003	0.27
13	64	1.4	.006	0.96	1.4	.006	0.95	2.4	.0005	0.39	2.1	.001	0.52
14	95	-	-	-	1.9	.002	0.71	-	-	-	-	-	-

The linkage peaks are bounded by the following SNPs: Chromosome 1: rs575962-rs1999755; Chromosome 2: rs348971-rs1198826; Chromosome 10: rs927099-rs1203406 (at 60 cM); rs1336439-rs1034178 (at 99 & 116 cM); Chromosome 13: rs1341518-rs5351; Chromosome 14: rs759364-rs872945;