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Binding Constants for the Complexes Between N-Hydroxy-IQ and Various Compounds in Tea*
Tea constituent
Kb (× 103 M−1)
EGC
1.1
EGCG
1.0
(+)-catechin
0.95
ECG
0.88
caffeine
<0.5
*
The mutagen was titrated with each tea constituent as shown in Figure 5, and the binding constant was determined from the Benesi-Hildebrand plot (Fig. 6).