Table 1.

Effect of hsREV3 antisense RNA level on cell killing and the frequency of 6-thioguanine-resistant mutants induced in human fibroblasts by UV

Cell line	Tet	Antisense level	UV, J/m2	Survival, %	No. of mutants	No. of cells selected × 10−6	Mutants per 106 cells selected*
10A	No	None	0	100	0	2.3	<3
			8	49 ± 8	45	6.0	38
			11	20 ± 10	88	6.0	64
10A-42	No	High	0	100	2	2.3	3
			8	38 ± 9	12	6.0	6
			11	22 ± 10	18	6.0	9

Data are from two independent experiments. 

*Corrected for cloning efficiency.