. Author manuscript; available in PMC: 2009 Feb 1.

Published in final edited form as: Neurobiol Dis. 2007 Sep 19;29(2):278–292. doi: 10.1016/j.nbd.2007.09.002

Table 1.

Meningioma and normal arachnnoidal tissue pairs

Meningioma line	Arachnoidal line	Patient diagnosis	Meningioma merlin expression^a	NF2 mutation^b
Meningioma line	Arachnoidal line	Patient diagnosis	Meningioma merlin expression^a	Exon	Sequence	Predicted result	LOH
MN302	AC006	sporadic	negative	10	c.947delT	FS	yes
MN307	AC007	NF2	low levels	15	c.1599_1602delGCAT	FS	ND
MN324	AC010	NF2	negative	UF	NA	NA	yes
MN327	AC012	NF2	low levels	4	c.447+1G>C	SP	ND
MN359	AC016	NF2	negative	12	c.1340+1insT	SP	ND

detection of low levels of merlin due to approximately 20% stromal contamination.

Mutations in italics are constitutional changes detected in a non-tumor tissue. FS-frameshift, SP-splice-site, NA-not applicable, UF-no mutation found by exon scanning, LOH-loss of heterozygosity of NF2 region markers, ND-not determined.