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. 2008 Feb 19;98(5):941–949. doi: 10.1038/sj.bjc.6604268

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Copyright © 2008 Cancer Research UK

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Immunohistochemical examination of Smac (A, C) and XIAP (B, D) in normal kidney (A, B) and RCC (C, D). In normal kidney, Smac expression was detected in tubular epithelial cells, Bowman capsule cells, and a portion of glomerular cells (A). In tumours, Smac staining was weaker than in normal kidney (C). XIAP expression was restricted to tubular epithelial and several glomerular cells in normal kidney (B).