Table 4. Standard SIR for high-risk malignancies according to adjuvant treatment.
SIR | 95% CI | P | |
---|---|---|---|
Leukaemia | |||
General population | 1 | ||
No adjuvant therapy | 0.99 | (0.14; 7.05) | 0.99 |
RT alone | 1.86 | (1.26; 2.73) | 0.0016 |
CT alone | 13.31 | (4.99; 35.46) | <0.0001 |
RT+CT | 3.63 | (2.06; 6.39) | <0.0001 |
Gynaecological cancer | |||
General population | 1 | ||
No adjuvant therapy | 0.89 | (0.13; 6.31) | 0.91 |
RT alone | 1.52 | (1.20; 1.92) | 0.0006 |
HT alone | 2.90 | (1.45; 5.80) | 0.0026 |
RT+HT | 2.39 | (1.67; 3.41) | <0.0001 |
Ovarian cancer | |||
General population | 1 | ||
No adjuvant therapy | 0.80 | (0.11; 5.70) | 0.82 |
RT alone | 1.46 | (1.07; 1.98) | 0.01 |
CT alone | 1.38 | (0.19; 9.77) | 0.75 |
RT+CT | 3.06 | (2.07; 4.53) | <0.0001 |
Abbreviations: CI=confidence interval; CT=chemotherapy; HT=hormonal therapy; RT=radiotherapy, SIR=standardized incidence ratio.