Table 4. Standard SIR for high-risk malignancies according to adjuvant treatment.

	SIR	95% CI	P
Leukaemia
General population	1
No adjuvant therapy	0.99	(0.14; 7.05)	0.99
RT alone	1.86	(1.26; 2.73)	0.0016
CT alone	13.31	(4.99; 35.46)	<0.0001
RT+CT	3.63	(2.06; 6.39)	<0.0001
Gynaecological cancer
General population	1
No adjuvant therapy	0.89	(0.13; 6.31)	0.91
RT alone	1.52	(1.20; 1.92)	0.0006
HT alone	2.90	(1.45; 5.80)	0.0026
RT+HT	2.39	(1.67; 3.41)	<0.0001
Ovarian cancer
General population	1
No adjuvant therapy	0.80	(0.11; 5.70)	0.82
RT alone	1.46	(1.07; 1.98)	0.01
CT alone	1.38	(0.19; 9.77)	0.75
RT+CT	3.06	(2.07; 4.53)	<0.0001

Abbreviations: CI=confidence interval; CT=chemotherapy; HT=hormonal therapy; RT=radiotherapy, SIR=standardized incidence ratio.