Table 3. Relative risk of colorectal adenoma for the offspring/sibling of individuals with colorectal cancer/adenoma.

	Colorectal adenoma
	Offspring	Sibling
	N	N
Location in parent/sibling	RR (95% CI)	RR (95% CI)
Invasive cancer
Colon	264	50
	2.59 (2.28–2.94)	2.64 (2.00–3.50)
Rectum	153	33
	2.59 (2.20–3.05)	2.75 (1.95–3.88)
Adenoma
Colon	30	36
	4.43 (3.09–6.34)	11.3 (8.15–15.7)
Rectum	25	19
	2.62 (1.77–3.89)	6.94 (4.42–10.9)

Bold signifies P<0.05.