Table 29.
Association Between Dietary Soy During Adolescence and Adult Breast Cancer
| Soy intake quintile (soy protein cut-off, g/day) | Adjusted OR (95% CI)a |
|
|---|---|---|
| Subject recall | Mother recall | |
| 1 (<2.20) | Reference | Reference |
| 2 (2.20–4.40) | 0.75 (0.60–0.93) | 0.70 (0.45–1.09) |
| 3 (4.41–6.60) | 0.69 (0.55–0.87) | 0.59 (0.32–1.07) |
| 4 (6.61–11.00) | 0.69 (0.55–0.86) | 0.60 (0.37–0.99) |
| 5 (≥11.01) | 0.51 (0.40–0.65) | 0.35 (0.21–0.60) |
| Trend test P value | <0.01 | 0.0002 |
a
OR adjusted for intake of rice and wheat products, education, family history of breast cancer, history of fibroadenomas, waist:hip ratio, age at menarche, physical activity, ever giving birth, age at first delivery, menopausal status, and age at menopause.
From Shu et al. (2001).