Table 30.

Statistically Significant Relationships Between Soy Intake and Breast Cancer^a

	Subjects, n		Adjusted OR (95% CI)
Exposure Group	Cases	Controls	b	c
Tofu intake of 1–3 times/week in adolescence	189	270	0.56 (0.38–0.82)	0.62 (0.42–0.92)
Tofu intake of ≥4 times/week in adolescence	55	85	0.51 (0.31–0.84)	0.65 (0.38–1.10)
Intake of >12.68 mg isoflavone/1,000 kcal in adulthood	104	166	0.51 (0.33–0.78)	0.61 (0.39–0.97)
High tofu intake in adolescence (≥1 time/week intake) and high isoflavone intake (>6.24 mg isoflavone/1000 kcal in adulthood)	164	261	0.53 (0.36–0.78)	0.65 (0.43–0.97)

^aFrom Wu et al. (2002)

^bAdjusted for birthplace, education, age at menarche, parity, current body-mass index, menopausal status, hormone use.

^cFurther adjusted for dark leafy green intake in adolescence, smoking, alcohol ingestion, physical activity, and family history of breast cancer.