Table 37.

Effects of Neonatal Exposures to Soy-Free Diet or Genistein on the Reproductive System of Male Rats^a

Effect	Soy-free control compared to standard-diet control	Genistein 4 mg/kg bw/day (soy-free diet) compared to soy-free control
Germ cell apoptotic index, PND 18	↔	↑
Germ cell apoptotic index, PND 25	↔	↔
Seminiferous tubule lumen formation, PND 18	↔	↓
Plasma inhibin B, PND 18	↔	↔
Sertoli cell nuclear volume/testis, PND 18	↑	↔
Plasma FSH, PND 18	↔	↓
Plasma FSH, PND 25	↔	↔
Spermatocyte/Sertoli cell nuclear volume, PND 18	↑	↓
Spermatocyte/Sertoli cell nuclear volume, PND 25	↑	↔

PND, postnatal day.

^a↑,↓ Statistically significant increase, decrease; ↔ no effect.

From Atanassova et al. (2000).