Table 46.
Effects on Adult Male Rats of Feeding Soy-Based Dieta
| Parameter | Comparison to phytoestrogen-free diet |
|---|---|
| Feed intake | ↔ |
| Water intake | ↑8% |
| Body weight | ↓5% |
| Prostate weight, absolute | ↓7% |
| Relative to body weight | ↓8% |
| Plasma hormone concentration | |
| Testosterone | ↓50% |
| LH | ↔ |
| Androstenedione | ↓85% |
| Estradiol | ↔ |
| Prostatic 5α-reductase activity | ↔ |
| Testicular steroidogenic acute regulatory protein | ↔ |
a
From Weber et al. (2001b). ↑, ↓, ↔ Statistically significant increase, decrease, or no change comparing male rats fed a soy-based diet containing total phytoestrogens 600 µg/g feed with male rats fed a phytoestrogen-free diet.