Table 3.

The effect of PK, Omez, and indomethacin as such and in combination with PK or Omez on the gastric secretion of pylorous ligated mice.^a

Mice	Gastric juice (ml) (6 h)	pH	Acid output (μEq/6 h)
Experimental control	0.85 ± 0.1	3.56	183.6 ± 6.8
Treated with PK	0.7 ± 0.1	3.41	179.2 ± 4.6
Treated with indomethacin	1.6 ± 0.2b	2.3	256.6 ± 10.2a
Treated with PK + indomethacin	1.3 ± 0.1c	3.46	206.2 ± 5.9c
Treated with Omez	0.75 ± 0.09	3.36	186.5 ± 6.8c
Treated with Omez + indomethacin	0.9 ± 0.12d	3.25	173.6 ± 6.4c

^aUntreated and treated mice were subjected to pylorous ligation. The treatment groups were orally administered PK (20 mg/kg/day × 3 days), Omez (3 mg/kg/day × 3 days), indomethacin (18 mg/kg × 1 d) as such or along with PK and Omez at the designated doses. The values are mean ± SEM (n = 5). ^aP < 0.05, ^bP < 0.01 compared to the experimental control mice ^cP < 0.05, ^dP < 0.01 compared to the indomethacin-treated mice