Figure 1.

Annual rate of change in BMD of the lumbar spine and total hip in premenopausal (red bars), early perimenopausal (blue bars), late perimenopausal (yellow bars), and postmenopausal (green bars) women (n = 1902). Rates of change were estimated from multivariable linear mixed models and adjusted for multiple covariates. Error bars represent 95% confidence limits. Comparisons were made across status categories: early peri- vs. premenopausal, P < 0.001 (spine) and P = 0.002 (hip); late peri- vs. early perimenopausal, P < 0.001 (spine) and P < 0.001 (hip); and post- vs. late perimenopausal, P = 0.002 (spine) and P < 0.001 (hip).