Table 2.
Molecular function or biological process classes of the genes differentially expressed in isolated islets
| Molecular or biological functions | No. of up-regulated genes (%) | No. of down-regulated genes (%) |
|---|---|---|
| Binding activity | 1161 (36) | 299 (33) |
| Transporter activity | 336 (10) | 88 (10) |
| Transcription regulator activity | 421 (13) | 123 (14) |
| Translation regulator activity | 99 (3) | 10 (1) |
| Signal transducer activity | 164 (5) | 68 (8) |
| Structural molecule activity | 78 (2) | 20 (2) |
| Enzyme and enzyme regulator activity | 449 (13) | 132 (15) |
| Catalytic activity | 102 (3) | 17 (2) |
| Receptor activity | 79 (2) | 22 (2) |
| Cell adhesion molecule activity | 49 (1) | 16 (2) |
| Inflammatory, immune, defense response genes | 47 (1) | 16 (2) |
| Apoptosis | 48 (1) | 10 (1) |
| Protein metabolism | 327 (10) | 71 (8) |
The number and percentage of differentially expressed transcripts within each functional class are reported.