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. Author manuscript; available in PMC: 2009 Feb 1.

Published in final edited form as: DNA Repair (Amst). 2007 Nov 26;7(2):253–266. doi: 10.1016/j.dnarep.2007.10.002

Fig. 4 — Frequency of IgM loss and mutation pattern in DT40 and derivatives deficient for XRCC3 or Brca1. (A) Frequency: Two independent experiments are shown. Each symbol represents the percentage of IgM-loss variants in an individual subclone after five weeks of culture. The median percentage of IgM-loss of all subclones of a particular genotype is plotted as a large dash, with the value indicated above each set. (B) Patterns of non-templated point mutations in Vλ, with or without selection for surface IgM phenotype. Raw numbers (% of total mutations).

Fig. 4 — Frequency of IgM loss and mutation pattern in DT40 and derivatives deficient for XRCC3 or Brca1. (A) Frequency: Two independent experiments are shown. Each symbol represents the percentage of IgM-loss variants in an individual subclone after five weeks of culture. The median percentage of IgM-loss of all subclones of a particular genotype is plotted as a large dash, with the value indicated above each set. (B) Patterns of non-templated point mutations in Vλ, with or without selection for surface IgM phenotype. Raw numbers (% of total mutations).