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. 2008 Jan 4;94(7):2566–2579. doi: 10.1529/biophysj.107.116673

FIGURE 3.

FIGURE 3

Effect of increasing the initial concentration of Elk-1 on ATF2 homodimers production. Elk-1 “trapping” of JNK1 and p38α, leaving less free p38* (a), results in a decrease in the production of activated ATF2 homodimers (b). Nonordered AND gate was assumed, initial condition: [p38] = [JNK] = 10 μM, [ATF2] = 30 μM. Initial concentration of Elk-1 varies between 0 and 50 μM, as indicated by the curves. The figure presents the concentration of produced homodimers disregarding reactions such as degradation, dissociation, etc.