Table 1.
vehicle | AP bursting | p value | |||
Current | peak current | pA | 607 ± 110 | 585 ± 82 | 0.83 |
peak current density | pA/pS | 8.49 ± 1.08 | 9.41 ± 1.00 | 0.54 | |
charge transfer | nC | 31.67 ± 6.60 | 25.95 ± 4.77 | 0.49 | |
τ on | s | 7.60 ± 1.14 | 8.21 ± 1.24 | 0.72 | |
τ off | s | 19.64 ± 3.49 | 16.92 ± 2.76 | 0.54 | |
left half width | s | 31.79 ± 3.73 | 39.27 ± 3.47 | 0.16 | |
right half width | s | 78.72 ± 13.94 | 77.15 ± 10.73 | 0.93 | |
Ca2+ | peak Ca2+ | nM | 600 ± 133 | 540 ± 121 | 0.75 |
Ca2+ 10 min later | nM | 270 ± 179 | 149 ± 51 | 0.46 | |
Ca2+ AUC | nM.s | 211 ± 79 | 152 ± 38 | 0.46 | |
left half width | s | 147 ± 101 | 105 ± 55 | 0.70 | |
right half width | s | 287 ± 150 | 159 ± 34 | 0.34 |
Charge transfer and area under the curve (AUC) were calculated from the integral of the trace between the current response onset and return to baseline and between the Ca2+ response onset and a point 10 min later. Current data comes from 9 vehicle and 10 AP bursting neurons of which Ca2+ data was recorded in 5 vehicle and 6 AP bursting cells. All Ca2+ analysis was performed from a somatic region of interest.