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Native low-density lipoprotein-induced macrophage migration is VEGFR1-dependent. VEGF or nLDL at the indicated concentrations was added to the lower chambers. Data were corrected for background intensities with no stimulation in WT mice and expressed as means±s.d. *P<0.001. Assays were carried out in triplicate. hpf, high-power field; nLDL, native LDL; LDLR, LDL receptor; VEGFR, vascular endothelial growth factor receptor; WT, wild type.
