Figure 1.

Sequence alignment of the Drp1 sequence surrounding the PKA phosphorylation site in the indicated species. The position of the PKA phosphorylation site in Drp1 identified by Chang & Blackstone (2007) and Cribbs & Strack (2007) is indicated by an asterisk, and the consensus sequence is shaded in yellow. The position of the Cdk1/cyclin B phosphorylation site (Taguchi et al, 2007) is indicated by an arrowhead, and the consensus sequence is shown in orange. Both the PKA and Cdk1/cyclin B phosphorylation sites are conserved in all species shown. Boundary amino-acid residues are indicated to the left. Numbering for the rat sequence is derived from Cribbs & Strack (2007). Cdk1, cyclin-dependent kinase 1; Drp1, dynamin-related protein 1; PKA, cAMP-dependent protein kinase.