Figure 1. Sialidase gene organization in zebrafish (Dr), fugu (Tr) and human (Hs).

Conservation of gene synteny around (A) neu1, (B) neu3 and (C) neu4 in zebrafish (Dr), fugn (Tr) and human (Hs). The arrows indicate the direction of gene transcription within each chromosome. Sialidase genes are depicted with grey arrows, while adjacent genes in syntenic regions are represented by black arrows. The size of the arrows is not proportional to that of the genes and the distances between genes are arbitrary. The white arrow indicates the human SPCS2 gene that appears to be absent from zebrafish and fugu genomes.